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What does progesterone do to a woman's body? It is secreted by the corpus luteum, a temporary endocrine gland that the female body produces after ovulation during the second half of the menstrual cycle. Progesterone prepares the endometrium for the potential of pregnancy after ovulation. It triggers the lining to thicken to accept a fertilized egg. Can I get pregnant with low estrogen levels? Low estrogen may lead to missed or irregular periods. Infertility: Low estrogen levels can prevent ovulation and make getting pregnant difficult, leading to infertility. Painful intercourse: Estrogen can affect vaginal lubrication. If levels become too low, vaginal dryness can occur, which often leads to painful sex. How long does HRT stay in your system after stopping? Many women stop taking HRT after about 5 years after they start taking HRT or soon after their symptoms are no longer a problem.
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